transparent-logo

A 64-year-old male presents to clinic with complaints of numbness and tingling in his right hand. The patient states that his symptoms have been ongoing for about 6 months and have been getting progressively worse. He endorses pain at night and states he occasionally wakes up from sleep to shake his hand out which helps relieve the pain. Examination reveals atrophy of the thenar eminence as well as decreased sensation to light touch in his thumb, index, and middle fingers. Which of the following is the most likely diagnosis?